Nature, Published online: 14 September 2026; doi:10.1038/s41586-026-11124-z Encoded and non-genetic protein variants expand human functional proteome

Nature, Published online: 14 September 2026; doi:10.1038/d41586-026-02895-6 A neural device uses artificial intelligence to read brain activity for intended words and gestures simultaneously.

Tyson Lake is a small pond on the upper edge of Piedmont at the top of Indian Gulch's watershed. It's invisible to everyone but the homeowners around it.

Disneyland's Big Thunder Mountain My next entry in the Geology of the Disney parks is Disneyland's Big Thunder Mountain. I am specifying that this is "Disneyland's" version of the ride because even though the ride has been replicated three other times in parks around the world (two of which also have the a centerpiece dinosaur skeleton), this one is unique to Disneyland. Here is the setup for the…

Nature Communications, Published online: 14 September 2026; doi:10.1038/s41467-026-77638-2 Treatment for frontotemporal dementia due to GRN haploinsufficiency (FTD-GRN) are lacking. Here, in this preclinical and Phase 1 clinical trial, the authors show that VES001, an oral small molecule sortilin inhibitor, is safe and well tolerated, and increased progranulin levels.

Nature Communications, Published online: 14 September 2026; doi:10.1038/s41467-026-74896-y Here, the authors show that coconut oil and the fatty acid myristic acid suppress Crohn disease-like intestinal inflammation in mice through multiple mechanisms, supporting a potential role for these dietary fats in promoting protective immune gut responses in Crohn’s disease.

Yesterday, Notre Dame Law School’s Lindsay and Matt Moroun Religious Liberty Clinic filed an emergency application to the U.S. Supreme Court. The application requests that the Court stay a New…

Mental health care use rose between 2019 and 2023, driven in part by increased symptoms of anxiety and depression, a study in Psychiatric Services has found.

Juergen Jaeger of Siemens EDA explains why hardware-assisted verification has since become a must-have. The post Hardware Assisted Verification Is Key to AI Chip Design appeared first on Semiconductor Digest .

Radioligand therapy (RLT) delivers therapeutic radionuclides to tumor-associated targets through specific targeting ligands and has demonstrated substantial clinical value in malignancies such as prostate cancer and neuroendocrine tumors. Beyond its direct induction of radiation-mediated tumor cell damage, RLT has attracted increasing attention for its potential immunomodulatory effects. Current …

Disappearing lakes and artificial intelligence are helping researchers gather data to map the thawing of permafrost across the globe.

Nvidia launches the RTX Pro 5500 Blackwell Workstation Edition graphics card for agentic and generative AI.

Yasmin is an advisor in our Advanced Technologies and Fusion Strategy team. Here she highlights the benefits of our new early engagement process and the Environment Agency’s role regulating the fusion industry. The Environment Agency, working alongside the Health and Safety Executive, is the regulator of fusion research sites and will jointly regulate future commercial …

Adobe is expanding Acrobat with Knowledge Base and Analyzer as it turns enterprise documents into context for AI-powered analysis and workflows.

Developing routines that work with the daily fluctuations of myasthenia gravis can complement treatment. Find out what experts recommend.

Wison Engineering Ltd. (Shanghai, China) and Axens (Rueil-Malmaison, France) signed a Memorandum of Understanding (MOU) to explore collaboration opportunities on selected e-SAF projects (sustainable aviation fuel, based on Fischer-Tropsch pathway). Through this framework, the two companies will jointly assess practical execution approaches that combine Axens’ process technology expertise and Wiso…

Consider a system of $3N$ particles with $p$ holonomic constraints: $$ g_v( \vec{r}_1 , \vec{r}_2 , ... , \vec{r}_N , t ) = 0 \, , \quad v = 1,2, ... , p \, .$$ Various textbooks state that the current spatial configuration of a system of $3N$ particles with $p$ holonomic constraints is determined by $3N-p$ independent coordinates $q_1,...,q_{3N-p}$ . Independent means that there is no relation o…