A study by researchers at the University of Birmingham has identified a new biomarker for response to a specific cancer therapy, treating children with Ewing Sarcoma and other tumor types.

I found the following two polynomial identities while experimenting with sums and differences of cubes. Identity 1 (sum of two cubes = perfect square): ...

Recently, the research group led by Dr. Dechao Feng, Lecturer at University College London (UCL) and Distinguished Research Fellow at Zhejiang Provincial People's Hospital, published a review entitled "Intratumoral Androgens and Genetic Variants Driving Therapy Resistance in Prostate Cancer".

This is a submission for the Gemma 4 Challenge: Write About Gemma 4 The Cloud is Great, But the Edge is Essential When we talk about the future of AI, the conversation almost always drifts toward massive data centers, hundreds of gigabytes of VRAM, and cloud APIs. But what happens when the cloud isn't there? In real-world crises—like the catastrophic floods that frequently hit South Asia—power gr…

The rapid adoption of AI coding assistants has fundamentally changed how software engineers write, debug, and explore codebases. Tools like Claude Code, Cursor, and Windsurf have made generating snippets and explaining logic near-instantaneous. However, as developers push these systems to handle larger engineering tasks—such as codebase-wide refactoring or porting legacy applications—they inevita…

This is a submission for the Gemma 4 Challenge: Build with Gemma 4 What I Built During major floods—like the catastrophic 2022 Pakistan Floods that displaced over 33 million people—mobile towers lose power and internet services collapse. This creates a critical communication blackout where stranded victims cannot signal for help, and rescue teams deploy boats, helicopters, and medical assets base…

Nature, Published online: 22 May 2026; doi:10.1038/d41586-026-01644-z Imaging suggests why the ability to make inferences declines after an episode of acute stress, such as a job interview.

Nature, Published online: 22 May 2026; doi:10.1038/d41586-026-01651-0 The late Hungarian mathematician Paul Erdős thought he had the last word on a geometry problem. Now an OpenAI chatbot has proved him wrong.

The Problem We Were Actually Solving We needed to support a large player base with thousands of concurrent players for the Treasure Hunt game mode. The game's event-driven architecture meant that every player movement, item pickup, and treasure collection triggered a flurry of events that needed to be processed quickly and efficiently by the server. The catch was that the event bus was prone to c…

A new review highlights how synthetic biology, AI, and spatial omics could transform ligand-receptor discovery from one-by-one searches into network-level mapping.

While many American adults are trying to reduce cholesterol levels, certain cancerous tumors have a relentless appetite for the metabolite.

I work on Camdiv , an anonymous one-to-one video chat. You open the page, you get matched with a stranger, you talk. It's the Omegle-style format, and from the outside the hard part looks like the video: WebRTC, NAT traversal, keeping latency down. It isn't. WebRTC is mostly a solved problem. The hard engineering is moderation. You're putting two anonymous strangers on a live camera together, wit…

It started, as side projects do, with another side project. I'd been playing with Hermes Agent and watching it produce things — reports, generated images, scraped CSVs, scratch notes. Useful stuff. And every time, the same nagging question: where does this go? The desktop wasn't going to cut it. Neither was a folder I'd forget about by Tuesday. I wanted somewhere I could throw anything at and tru…

Most ASP.NET Core logging setups tell you that something failed — but not what actually happened during the request lifecycle. I built AsGuard to provide lightweight request + exception logging with a built-in dashboard and minimal setup. GitHub Repository: https://github.com/mahmood-alsarraj/asguard Why AsGuard? centralized request + exception visibility built-in dashboard minimal setup easier i…

PurposeRikkunshito, a traditional Japanese herbal medicine, is used to improve gastrointestinal (GI) function. However, its mechanisms of action in irritable bowel syndrome (IBS) remain unclear. This study aimed to investigate the effects of Rikkunshito on colonic pacemaker activity, inflammation, GI hormones, pain-related behaviors, and transient receptor potential (TRP) channel activity in a zy…

BackgroundKnee osteoarthritis (KOA) is characterized by the progressive degeneration of articular cartilage, necessitating novel therapeutic strategies to halt disease progression. Isoviolanthin, a natural flavonoid glycoside, has an unclear mechanism of action in KOA.MethodsWe employed network pharmacology and molecular docking, supported by in vitro assays, to investigate the mechanisms of isov…

npj Climate and Atmospheric Science, Published online: 22 May 2026; doi:10.1038/s41612-026-01441-5 Intensification of summer mesoscale convective systems in East China under global warming

npj Climate and Atmospheric Science, Published online: 22 May 2026; doi:10.1038/s41612-026-01437-1 Adaptive expert-guided deep imbalanced regression for global PM2.5 forecasting with temporal convolutional networks and GEOS-FP inputs

Cannes film festival: This could be better paced but the crisis which descends on an up-against-it dairy farm is delivered by some very memorable goons There’s nothing like a home-invasion suspense thriller to provide a change of pace in the Cannes competition, and Léa Mysius’s film – adapted from the French bestseller Histoires de la Nuit by Laurent Mauvignier – isn’t at all bad, although it run…

A sharp-eyed satellite captured an amazing photo of SpaceX's first Starship V3 megarocket on the pad Thursday (May 21), just before it was supposed to lift off.