Nature Communications, Published online: 31 August 2026; doi:10.1038/s41467-026-77041-x Anti-HER2 antibody-drug conjugates (ADCs) have been approved for patients with Hormone Receptor positive (HR + ), HER2-low metastatic breast cancer. Here, the authors present a phase II interventional clinical trial evaluating the anti-HER2 ADC SHR-A1811 as neoadjuvant monotherapy in patients with HR + HER2-lo…

Ambrian Energy GmbH and Messer SE & Co. KGaA announce that the planned joint venture “CarbonBridge” has successfully received antitrust approval from the European Commission. This milestone paves the way for the development of the terminal of the same name — Germany’s first operational CO₂ export te...

Plozasiran treatment resulted in substantial reductions in triglyceride levels in patients with severe hypertriglyceridemia after one year, according to results presented in a Hot Line session today at ESC Congress 2026 and published simultaneously in the New England Journal of Medicine.

New federal rules mean Arizona will be getting a lot less water from the Colorado river. City leaders say they've been planning for years and no one will run out, but keeping taps flowing is expensive.

My concrete problem is that I want to calculate cross-sections for photoionization transitions in argon in Python. For example from the excited state 3S^23p^56d into the continuum. For this, I found Cooper-Zare theory in several sources, including "Introduction to Photoelectron Angular Distributions". The formula for the cross section is, according to the above-mentioned book(p.87): (i am doing s…

Insider Brief FedEx and Dexterity are expanding their collaboration to deploy Dexterity’s Foresight world model and Mech trailer-loading robots at the FedEx Hagerstown Hub in Maryland, moving the technology beyond an earlier pilot into larger-scale operations. According to the companies, the deployment builds on several years of joint development, testing and operational validation. The Hagerstow…

Most AI agent demos work beautifully. Then they hit real users, real data, and real edge cases — and start booking the wrong meetings, leaking context, or looping forever on a task they can't finish. The gap between "impressive demo" and "dependable system" is almost never the model. It's the guardrails around it. This is a practical guide to why agents fail once they leave the demo, and the conc…

Teaching an AI agent to upgrade .NET, React, and Next.js apps for real — not just talk about it Every engineering team has that repo. The one running a framework version from three or four years ago. Everyone knows it needs an upgrade. Nobody wants to be the one who breaks production doing it. That's the problem UpgradePilot — an open-source, multi-agent upgrade pipeline — is built to solve. And …

On August 26, the Shanghai municipal government released its 15th Five-Year Plan for the Development of Strategic Emerging Industries, setting a target for added value in strategic emerging industries to reach CNY2.1 trillion (approx. US$312.5 billion) by 2030. The plan puts ICs, biopharmaceuticals, and artificial intelligence (AI) at the center of the city's industrial strategy, while shifting p…

An editorial in Diabetology International argues that inappropriate GLP-1 use should be judged not only by regulatory compliance or off-label prescribing, but also by whether weight reduction is medically safe, nutritionally adequate, and properly supervised. Drawing on Japanese reports of ketosis and ketoacidosis following inappropriate tirzepatide use, the authors call for greater attention to …

An inconvenient 12-hour trip made me rethink what we should—and shouldn’t—outsource to AI.